Head coach Kyle Shanahan sits down with Greg Papa on "49ers Game Plan" to discuss the development of rookie Isaac Guerendo ...

For San Francisco, tight end George Kittle (hamstring) is doubtful, defensive end Nick Bosa (rib) and cornerback Charvarius ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...

San Francisco 49ers star Deebo Samuel has launched his own show — Cleats & Convos with Deebo Samuel — and on his debut ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

Deebo Samuel's debut as a podcaster didn't go so well. He and his guest Brandon Aiyuk barely spoke, and when they did speak, ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

San Francisco 49ers star Deebo Samuel debuted his new podcast Tuesday and was quickly met with a litany of bad reviews on X ...

Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t ...

Keyshawn Johnson breaks down Deebo Samuel’s claim that it's 'Now or Never' for the San Francisco 49ers to win the Super Bowl.

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

The San Francisco 49ers offense was dealt another blow with star receiver Deebo Samuel getting sidelined by a strained calf.