With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

Kyle Shanahan explained to NBC Sports Bay Area’s Greg Papa on “49ers Game Plan" why San Francisco's offense won’t change ...

The 49ers are likely to be without George Kittle, Christian McCaffrey and Deebo Samuel for Sunday's game at the Rams.

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

Two of the best wide receivers in the NFL are expected to be on the field for their respective Week 3 games. Justin Jefferson ...

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

The San Francisco 49ers are unlikely to have tight end George Kittle when they take on the Los Angeles Rams on Sunday at SoFi ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

San Francisco 49ers running back Christian McCaffrey will be eligible off the injured reserve after Week 6, but could still miss a pivotal Week 7 Super Bowl rematch with the Kansas City Chiefs.